Swearing revenge, the doctor sought two things: his former colleagues and to assume his human form once again. Caine was disposed of by means of chemical waste, but little did his former colleagues know that the chemicals did not kill him instead, they altered him into the angry, sentient, amorphous creature known as 'The Ooze'. But, in the process, the Directorate of the company burst in, angry that the doctor had stumbled upon his plot. Crane discovered that his colleagues were planning to release a plague upon the populace, and make a fortune as they held the only cure. Daniel Caine, a brilliant scientist who invented an achromatic odorless toxic gas and its antidote, sneaking into the research lab where he worked in order to find evidence that crimes were being conducted by using the toxic gas he created. The plot recalls numerous elements of the cult film The Toxic Avenger. However some of the programming was fairly advanced for a 16-bit system, for example the speed powerup effect was actually created by decreasing the viscosity of the character. Giger necessitated by the constraints of the medium. The Ooze is unique in that the central character or protagonist is based on an algorithmically-generated cellular automaton, and as such, the player character can be split apart and reformed like a viscous liquid.

The Ooze is something a cult favourite in recent times and has been included in numerous retro gaming compilations. Dave Sanner of Sega of America, who was also behind the game Sonic Spinball, came up with the unique concept for The Ooze and was its lead programmer. The Ooze is a video game developed by Sega Technical Institute for the Mega Drive/Genesis console and was released in 1995 during the latter days of the console.

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